S-2238, which is specific to thrombin, is a short peptide covalently bound to pNA (4-nitroaniline). When attacked by thrombin, it gives up a free pNA which could be detected by a spectrophotometer at 405 nm.
S-2238 is mainly used in anti-FIIa activity assay of heparin.
S-2238 can be used in many applications, such as:
S-2238 is white lyophizied powder, stored in vials.
Each vial contains: S-2238 10 mg (15 μmol); mannitol 120 mg.
Synonyms: S-2238, thrombin substrate
CAS number: 113711-77-6
Molecular formula: H-D-Phe-Pip-Arg-pNA·2HCl
Molecular weight: 625.6 Da
Purity: ≥ 99% (HPLC)
Absorption coefficient: A405nm ≤ 0.120 [L/(g·cm)]
Solubility: > 10 mg/mL (in pure water)
Reconstitute the entire contents of a vial, dissolve it with 5 mL distilled water to get a solution with concentration of 3 mmol/mL S-2238.
The lyophilized powder of S-2238 could be preserved at 2 to 8 ℃ for at least 24 months.
The 3 mmol/mL S-2238 solution could be preserved at 2 to 8 ℃ for about 1 month.
Catalog number: AG00-0101
Package size & price:
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S-2238 is only used for lab researches. Do NOT use it as drugs or in vivo experiments.
See more about chromogenic assays.
Click the links to see the anti-FIIa assay for low-molecular-weight heparins.